SMaHRT (Stroke Motor reHabilitation and Recovery sTudy) is a longitudinal study aimed at understanding the natural history of upper extremity motor recovery after ischemic stroke. Participants will be enrolled during their acute stroke hospitalization and will have research visits spanning the post-stroke care continuum at 6 weeks, 3 months, 6 months, and one year. These research visits will be integrated with comprehensive clinical visits to the Stroke Motor Recovery Clinic of the Center for Neurotechnology and Neurorecovery (CNTR, cntr.mgh.harvard.edu). The study will collect clinical outcome measures, video- and robot- based kinematic data, smartphone usage patterns, as well as EEG data in order to quantify the course of motor recovery. The ultimate goal is to rigorously understand the behavioral, neuroanatomic, and neurophysiologic underpinnings of recovery in order to develop personalized strategies and neurotechnologies to facilitate neurorehabilitation and enable better recovery for our patients.
In its first 3 months, the study has enrolled 25 participants (as of Aug 29, 2017). The ultimate goal is to enroll a minimum of 100 participants over a two-year period. Patients must be aged 18 to 80 and present to MGH with an acute ischemic stroke resulting in upper extremity motor weakness. Participants must be able to follow simple commands in English, must have no prior major developmental, neurological, or psychiatric disorder, and must be willing to obtain their follow-up care at MGH.