SMaHRT (Stroke Motor reHabilitation and Recovery sTudy) is a longitudinal study aimed at understanding the natural history of upper extremity motor recovery after ischemic stroke. Participants will be enrolled during their acute stroke hospitalization and will have research visits spanning the post-stroke care continuum at 6 weeks, 3 months, 6 months, and one year. These research visits will be integrated with comprehensive clinical visits to the Stroke Motor Recovery Clinic of the Center for Neurotechnology and Neurorecovery (CNTR, cntr.mgh.harvard.edu). The study will collect clinical outcome measures, video- and robot- based kinematic data, smartphone usage patterns, as well as EEG data in order to quantify the course of motor recovery. The ultimate goal is to rigorously understand the behavioral, neuroanatomic, and neurophysiologic underpinnings of recovery in order to develop personalized strategies and neurotechnologies to facilitate neurorehabilitation and enable better recovery for our patients.

In its first 3 months, the study has enrolled 25 participants (as of Aug 29, 2017). The ultimate goal is to enroll a minimum of 100 participants over a two-year period.   Patients must be aged 18 to 80 and present to MGH with an acute ischemic stroke resulting in upper extremity motor weakness. Participants must be able to follow simple commands in English, must have no prior major developmental, neurological, or psychiatric disorder, and must be willing to obtain their follow-up care at MGH.

The SMaHRT Team

Leigh Hochberg, MD, PhD, Principal Investigator

David Lin, MD, Co-Investigator

Alison Cloutier, MS, Clinical Researcher

Yuliya Mironovas, MA, Project Coordinator

Jonathan Rosand, MD, MSc, Chief, Division of Neurocritical Care and Emergency Neurology

Seth Finklestein, MD, Stroke Neurologist

Kelly Sloane, MD, Vascular Neurology Fellow

Jessica Ranford, MS, OTR/L, Occupational Therapist, Clinical Specialist

Kristin Parlman, PT, DPT, NCS, Neurologic Clinical Specialist

Kim Erler, PhD, OTR/L, Assistant Professor, School of Health and Rehabilitation Sciences, MGH Institute of Health Professions

Jessica Asiello, MS, OTR/L, Occupational Therapist

Kimberly Cortina, MS, OTR/L, Occupational Therapist

Helena Diodati, MS, OTR/L, Occupational Therapist

Natasha Frazier, MS, OTR/L, Occupational Therapist

Caitlin McCusker, MS, OTR/L, Occupational Therapist

Abigail Rude, MS, OTR/L, Occupational Therapist

Kristen Andrew, PT, DPT, Staff Physical Therapist

Meaghan Costello, PT, DPT, NCS, Staff Physical Therapist

Erin Greenler, PT, DPT, NCS, Staff Physical Therapist

Kirstie Hinsman, PT, DPT, NCS, Staff Physical Therapist

Jana Strom, PT, DPT, NCS, Staff Physical Therapist

Danielle K. Kline, PT, DPT, NCS, Physical Therapist, Neurologic Clinical Specialist, PhD Research Fellow in the Brain Recovery Lab at MGH Institute of Health Professions

Galina Gheihman, Medical Student, Harvard Medical School

Sean Scholwater, Medical Student, Boston University Medical School

SMaHRT Collaborators

Susan Fasoli, ScD OTR/L, Associate Professor, MGH IHP Department of Occupational Therapy

Nicole Mazwi, MD, Co-Director, Brain Injury Medicine Fellowship Program, Department of Physical Medicine and Rehabilitation Spaulding Rehabilitation Hospital, Co-Director, Neurorecovery Fellowship Program, Department of Neurology Massachusetts General Hospital

SMaHRT Alumni

Fabio Giatsidis, MD, Clinical Research Fellow

Massachusetts General Hospital and Harvard Medical School